This case report was presented the clinical, ultrasonographic, biochemical, hematological, urinary, periteonal fluid and histopathological finding in a dog with hepatic failure. Blood RBC, Hct, Hbg, MCV ve MCHC values were significantly decreased. While Serum AST ve ALT levels were determined significant increased, serum BUN, creatinin, TP, albumin and cholesterol concentrations were determined significant decreased. In the ultrosongrafic examination, hetoregen hyperechogenicity of Iiver parenchyma was observed.