1992, Cilt 8, Sayı 2, Sayfa(lar) 074-076 |
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The Comparative Study On Acut Renal Toxicity Of ionic And Non-ionic Contrast Media In Cell Culture |
Sibel Yavru1, Nuri Yavru2 |
1Yard. Doç. Dr., S.Ü. Veteriner Fakültesi, Viroloji Bilim Dalı, Konya 2Doç. Dr., S.Ü. Veteriner Fakültesi Cerrahi Anabilim Dalı, Konya |
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In this study was carried out to show the damage of high osmolality ionic and low osmolality non-ionic contrast media in indirect radiography of kidneys, invitro.
In this study MDBK was used as permanent cell culture. Omnipaque (lohexol) which is low osmolality non-ionic and Urografin 76 % (Diatrizoate) which is high osmolality ionic contrast media were used in different dilution con-cdntrations. As a result ionic contrast media even in low concentration produced CPE in kidney cell culture, but alternatively the same effect .was determined in non-ionic media after 24 hours without any dilution. CPE was not determined in cell cultures dilution of these media. |
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