Alloxan was given to the each dog at the rate of 0.60 mmol/kg and plasma glucose, aspartat amino transferase (AST), total protein (TP), Na and K values were determined in the collected blood samples in'the different days before and after alloxan injection.

At the beğining of the study these values were found to be 4.18±0.22 mmol/l, 13.89 ±3.19 U/l, 43.7± 3.09 g/l, 153,40±4.74 mEq/land4.64±0.6mEq/lrespectively whereas they found as 15.31 ± 1.22 mmol/l, 20.20 ±2.21 U/l, 51.3 ± 3.01 g/l, 151.46 ± 11.2 mEq/l and 4.08 ± 0.43 mEq/l at the end of the study respectively. Only the differences of glucose values were statistically significant (P < 0.01) in the analysed parameters.