Mortality, swollen face and oculer tissue, bristled up feathers and some decrease on the consumption of drinking water and feed were observed in turkeys brought from two different flocks (a number 1500 aged 55 days and 800 aged 16 days). Rates of serum positive 40 % (aged 16 days) and 70 % (aged 55 days) were determined by rapid agglutination test from the samples collected from two flocks. Ornithobacterium rhinotracheale was isolated from the samples collected from alungandanair sacs of a turkey aged 55 days. The O. rhinotracheale strain was found to be susceptible to amoxcilline and combinations of amoxicilline+clavulonic acid and kanamisin+cephalexin. This is the first report on the presence of O. rhinotracheale infection in turkeys from Turkey.